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Protein To Reduce Spread Of Cancer Identified
Know about a protein that helps in reducing the spread of cancer here in this article.
Cancer is believed to be one of the deadliest disease. Cancer is something that when you just hear about the word, it sends some shrill feeling in our m ind. If not taken care of on time cancer can turn fatal as well.
In a new study, researchers have found a new protein that could reduce the spread of cancer by binding the cancer cells together and allowing them to invade tissues.
The study was conducted by the researchers from University of Guelph, Ontario. During the study, the researchers have identified a protein called cadherin-22, a potential factor in cancer metastasis or the spread of cancer.
In addition to this the protein also decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 per cent.
"Cadherin-22 could be a powerful prognostic marker for advanced cancer stages and patient outcomes. If you can find a treatment or a drug that can block cadherin-22, you could potentially prevent cancer cells from moving, invading and metastasizing" said lead author Jim Uniacke, a professor at the varsity.
During the course of the study, researchers found that it is precisely under conditions of low oxygen that cancer cells trigger the production of cadherin-22, putting in motion a kind of protein boost that helps bind cells together, enhancing cellular movement, invasion and likely metastasis.
Studying breast and brain cancer cells in a hypoxia incubator, the researchers discovered that cadherin-22 is involved in this process to enable the spread of cancer cells.
For both cancer types, the research team used molecular tools to reduce the amount of cadherin-22.
They placed the human cancer cells into the incubator and lowered the oxygen to a level comparable to that in a tumour. The cells failed to spread.
One very powerful and common tool in cell and molecular biology labs is, you can remove a protein from a cell and see how that cell behaves without it.
The study was recently published in the journal Oncogene.
Meanwhile, listed here are a few of the best cancer fighting foods. Take a look.
1.
Broccoli:
Broccoli
is
one
of
the
best
known
cruciferous
vegetables.
It
contains
a
compound
called
glucosinolates,
which
produce
protective
enzymes
in
the
body.
Sulforaphane
is
one
of
the
enzymes
that
helps
reduce
cancer
risk
by
flushing
out
cancer-causing
chemicals.
2.
Green
Tea:
Green
tea
contains
important
compounds
like
catechins,
xanthine
derivatives,
epigallocatechin-3-gallate
(EGCG)
and
epicatechin.
These
compounds
help
prevent
the
development
of
cancerous
cells.
In
addition
to
this,
green
tea
also
help
in
preventing
free
radicals
from
damaging
cells.
3. Ginger:
Known for its antioxidant properties, ginger helps in fighting the cancer cells. Drink 2-3 cups of ginger tea on a regular basis or you could also add ginger in your daily diet.
4.
Garlic:
Garlic
contains
certain
compounds
like
arginine,
oligosaccharides,
flavonoids
and
selenium
which
are
known
to
fight
the
risk
of
cancer.
Add
garlic
to
your
daily
food
or
you
could
also
take
garlic
in
the
form
of
supplements.
(With Agency Inputs)
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