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Group B Streptococcus (GBS) Disease: Causes, Symptoms, Diagnosis, Treatment And Prevention
July is International Group B Strep Awareness Month, which is observed to create awareness about group B strep disease to the general public. The theme for this year is '2020 foresight'.
What Is Group B Strep?
Group B Streptococcus (group B strep or GBS), also known as Streptococcus agalactiae, is a gram-positive bacteria that often stay in the body of healthy adults, especially in the gastrointestinal tract and genitourinary tract (urinary and genital organs). This bacteria is usually harmless, however, it can cause serious illness known as group B streptococcal disease in elderly people and people with underlying diseases [1].
According to the American Pregnancy Association, this bacteria is normally present in the vagina or rectum in about 25 per cent of all healthy adult women. In pregnant women, group B strep colonisation (carriers of the bacteria)increases the risk of group B strep disease in newborns [2].
Causes Of Group B Strep Disease [3]
In
many
healthy
adults,
group
B
strep
bacteria
normally
live
in
the
gastrointestinal
and
genital
tracts.
But,
sometimes
the
bacteria
invade
the
body
and
cause
certain
infections.
From
the
mother,
group
B
strep
can
spread
to
a
newborn
during
delivery
or
while
the
baby
is
in
the
uterus.
In
this
way,
the
bacterial
infection
is
transmitted
from
the
colonised
mother
to
her
newborn.
However,
not
all
babies
will
be
affected
by
the
bacteria.
How
people
get
these
bacteria
and
spread
to
others
is
not
known.
Symptoms Of Group B Strep Disease
The signs and symptoms of group B strep disease differ from newborns to adults [4].
In newborns and mothers the symptoms are:
•
Fever
•
Breathing
difficulty
•
Bluish
skin
colour
•
Difficulty
in
feeding
•
Irritability
or
fatigue
(hard
to
wake
up
the
baby)
In babies, the early onset of GBS infections occurs within the first week of life and babies who develop the disease later have it after the first week of life.
In adults the symptoms are:
•
Fever
•
Chills
•
Decrease
in
alertness
•
Cough
•
Difficulty
in
breathing
•
Chest
pain
•
Skin
and
soft
tissue
infections
•
Bone
and
joint
infections
Risk Factors Of Group B Strep Disease
In pregnant women, the factors that can increase the risk of having her baby to develop GBS disease are: [5]
•
If
you
tested
positive
for
group
B
strep
bacteria
during
late
pregnancy.
•
If
you
have
fever
during
labour.
•
The
mother's
water
breaks
18
hours
or
more
before
delivery.
•
The
mother
has
a
urinary
tract
infection
during
pregnancy.
•
The
mother
previously
delivered
a
baby
with
GBS
disease.
In adults, the risk factors of GBS disease are:
•
Obesity
•
Diabetes
•
Heart
disease
•
Cancer
or
history
of
cancer
•
Congestive
heart
failure.
•
If
you
are
65
years
or
older.
Complications Of Group B Strep Disease
•
Babies
can
become
deaf
and
develop
disabilities.
•
Miscarriage
[6]
•
Stillbirths
[7]
•
Preterm
deliveries.
•
GBS
bacteremia
[8]
•
Pneumonia
[8]
•
Meningitis.
•
In
some
cases,
death.
Diagnosis Of Group B Strep Disease
For diagnosing GBS disease, the doctor will collect samples of blood and spinal fluid and then will check the samples to see if the GBS bacteria are growing in it. In addition, the doctor may conduct chest x-ray to help determine if the person has GBS disease. If GBS bacteria caused urinary tract infection, then the doctor will collect samples of urine to check for urinary tract infections [9].
Treatment Of Group B Strep Disease
Intravenous penicillin G and ampicillin antibiotics are used for the treatment of GBS disease. The dose for penicillin G is 5 million units followed by 2.5 to 3 million units given every four hours during labour until delivery. And the dose for ampicillin is 2 gm followed by 1 gm which is given every four hours during labour until delivery [10].
Antibiotics are given to women who are at an increased risk of having a baby with group B strep disease and aids in protecting the baby from infection, but only if it's given during labour.
Prevention Of Group B Strep Disease
•
Women
should
get
tested
for
GBS
infection
between
the
35th
and
37th
week
of
pregnancy.
•
Intravenous
antibiotics
are
recommended
for
pregnant
women
during
labour
to
lower
the
risk
of
GBS
infection
[11].
To Conclude...
Although GBS disease is rare, with proper treatment and preventive methods, one can overcome the disease. Currently, there's no vaccine to protect pregnant women and newborns from GBS bacteria, but researchers are working to develop a vaccine.
Common FAQs
Q. What happens if you test positive for group B strep?
A. If you have been tested positive for group B strep, this means that you are a carrier of the bacteria and it may transmit to the baby. However, in some cases a mother who tests positive, her baby might not get affected by the bacteria.
Q. Is group B strep contagious to your partner?
A. No, group B strep is not a sexually transmitted disease.
Q. How can I protect my baby from group B strep?
A. All pregnant women should get tested for group B strep between 35 to 37 weeks of every pregnancy. And if you have been tested positive for group B strep, the doctor will give you intravenous antibiotics to lower the risk of your baby developing early-onset group B strep infection.
Q. Is group B strep and strep throat same?
A. No,Group B Streptococcus (group B strep) should not be confused with group Astreptococcus that causes strep throat.
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