Just In
- 9 hrs ago Anant Ambani-Radhika Merchant's Wedding Function Details Are Out, Check out Ambani Bahu-To-Be's Chic Fashion!
- 9 hrs ago Nayanthara Poses With Husband Vignesh Shivan In Chic Saree, Check Her Sarees To Ace Summer Wedding Look
- 13 hrs ago Hanuman Jayanti 2024: These Are Lord Hanuman's Favourite Zodiac Signs, Check Out The List!
- 14 hrs ago Arushi Sharma-Vaibhav Vishant Wedding, Love Aaj Kal 2 Actor Looks Resplendent In A Pastel Ethnic Outfit, Pics!
Don't Miss
- Technology Apple Confirms Special Event for May 7: iPad Air, iPad Pro 2024 Models Expected
- Finance TCS Vs Infosys Vs Wipro Shares, ADRs, Upcoming Dividends: Which Mega IT Stocks To Buy After Q4 Results?
- Sports Who Won Yesterday's IPL Match 39? CSK vs LSG, IPL 2024 on April 23: Marcus Stoinis Fires 63-ball 124 To Quiet Chepauk
- News Senator Lambie Calls For Elon Musk's Imprisonment Over Wakeley Church Stabbing Posts
- Movies Mirzapur 3 OTT Release Date, Platform: When Will Mirzapur Season 3 Premiere On Amazon Prime Video?
- Education Telangana Inter Manabadi 1st and 2nd Year Results 2024 to be Declared Tomorrow
- Automobiles Chrysler Pacifica Marks Seven Years As Most Awarded Minivan With New Campaign
- Travel Kurnool's Hidden Gems: A Guide To Exploring India's Lesser-Known Treasures
Covid-19 Vaccine Protects People Of All Sizes: Lancet Study
COVID-19 vaccines greatly reduced the number of cases of severe COVID-19 for everyone regardless of their body size, according to a study of 90 lakh adults in England published in The Lancet Diabetes and Endocrinology on Friday. Vaccine effectiveness was similar for those with a higher body mass index (BMI) and of a healthy weight, but slightly lower in the underweight group, who were also the least likely to have been vaccinated, the researchers said.
In a further analysis of vaccinated people only, among the fewer COVID-19 cases recorded, people of very low and very high BMI were more likely to experience severe disease than vaccinated healthy weight people, they said."Our findings provide further evidence that COVID-19 vaccines save lives for people of all sizes," said study lead author Carmen Piernas from the University of Oxford, UK.
"Our results provide reassurance to people with obesity that COVID-19 vaccines are equally as effective for them as for people with a lower BMI, and that vaccination substantially reduces their risk of severe illness if they are infected with COVID-19," Piernas said.
The data also highlights the need for targeted efforts to increase vaccine uptake in people with a low BMI, where uptake is currently lower than for people with a higher BMI, the researchers said.
They searched anonymised health records from more than 12 million patients in England taking part in QResearch - a secure database of healthcare information available to verified researchers.
Of these, 9,171,524 (9.1 lakh) patients who were over 18 years old, had BMI data, and had not previously been infected with SARS-CoV-2 were included in the study.
People were grouped based on their BMI according to four World Health Organisation definitions of 18.5-24.9 kilogrammes per square metre (kg/m2) for a healthy weight, below 18.5 for underweight and 25- 29.9 for overweight.
Characteristics such as age, sex, smoking status, and social deprivation were also accounted for in the analyses. Of over 90 lakh people included in the study, 566,461 (over 5.6 lakh) tested positive for SARS-CoV-2 during the study from December 8, 2020 (date of the first vaccine given in the UK) to November 17, 2021.
Of those, 32,808 were admitted to hospital and 14,389 died.
At the end of the study period, 23.3 per cent of the healthy weight group, 32.6 per cent of the underweight group, 16.8 per cent of the overweight group and 14.2 per cent of the group with obesity had no doses of any COVID-19 vaccine.
To understand vaccine effectiveness, the researchers compared the risk of severe disease in vaccinated versus non-vaccinated people at least 14 days after a second dose.
They found that being vaccinated offered high protection across all BMI groups, but that the effect was slightly lower in underweight people.
Underweight vaccinated people had around half the likelihood of being hospitalised or dying compared with unvaccinated people of the same BMI.
In comparison, people in the healthy and high BMI groups who were vaccinated were around 70 per cent less likely to be hospitalised than unvaccinated people, the researchers said.
People with a healthy or a higher BMI were also around two-thirds less likely to die than their unvaccinated counterparts two weeks after a second dose, they said.
- disorders cureCommon COVID Symptoms In Fully Vaccinated Individuals: What You Should Know
- wellnessMild COVID Linked To Life-Threatening Blood Clots, Increased Risk Of Cardiovascular Disease; Study
- wellnessCOVID-19 Variants In India: New COVID Variant May Pose Threat To Elderly People
- basicsCovid-19 Linked To Early Onset Of Periods: What You Need To Know
- wellnessCOVID XBB Variants Of Omicron In India: What You Should Know
- disorders cureNew Omicron Subvariant BQ.1 Detected In Maharashtra: What You Should Know
- disorders cureOmicron BF.7 In India, Risk Of Fresh Wave During Diwali: What You Should Know
- disorders cureWhat Is ‘Centaurus,’ New Fast-Spreading Covid Variant: Everything You Need To Know
- health75 Years Of Independence, 75 Days Of Free COVID Booster Shots; For Everyone Aged 18-59 From 15 July
- wellnessWhat Are The Health Risks Of Getting COVID The Second Or Third Time? 7 Important Points
- wellnessGovt Panel Recommends Emergency Approval For SII's Covovax For 7-11 Year Olds
- wellnessHow Does COVID Spread During Short Conversations?