- 4 hrs ago Children Inherit Intelligence Mainly From Their Mothers: How Far Is It True?
- 6 hrs ago Single Foster Dad Adopts Five Children To Ensure They Stay United As A Family
- 7 hrs ago Indian Festival Of Holi In Germany: The Colourful Summer Party
- 9 hrs ago Guru Hargobind Singh Birth Anniversary 2022: Interesting Facts About The Sixth Guru Of The Sikhs
- Sports High jumper Tejaswin Shankar to be part of Indian contingent for CWG 2022: AFI tells HC
- Finance Emkay Global Bets On This Maharatna Stock For 36% Potential Gains, Details Inside
- News SC refuses to cancel bail granted to Malayalam film producer Vijay Babu in sexual assault case
- Movies Lock Upp Fame Payal Rohatgi Looks Resplendent In Pink Bandhani Suit At Her Mehndi Ceremony; SEE PICS
- Automobiles Hyundai Teases New N Concept & Ioniq 5 N Ahead Of July 15 Debut
- Technology Lava Blaze Pre-Orders To Debut On July 7 In India: Should You Book?
- Education TBSE 10th, 12th Result 2022 Declared At tbresults.tripura.gov.in, Check Tripura Madhyamik, HS Result
- Travel Great Barrier Reef: Planet's Natural Ornaments
Breathing in polluted air could lead to toxic particles being transported from lungs to brain, potentially contributing to brain disorders and neurological damage, according to a study.
An international team of scientists from the University of Birmingham, UK, and institutions in China found a possible direct pathway used by various inhaled fine particles through blood circulation with indications that, once there, the particles stay longer in the brain than in other main metabolic organs.
The study, published in the journal PNAS on Monday, found various fine particles in human cerebrospinal fluids taken from patients who had experienced brain disorders -- uncovering a process which may result in toxic particulate substances ending up in the brain.
"There are gaps in our knowledge around the harmful effects of airborne fine particles on the central nervous system," said study co-author Iseult Lynch, a professor at the University of Birmingham.
The finding sheds new light on the link between inhaling particles and how they subsequently move around the body.
"The data suggests that up to eight times the number of fine particles may reach the brain by travelling, via the bloodstream, from the lungs than pass directly via the nose -- adding new evidence on the relationship between air pollution and detrimental effects of such particles on the brain," Lynch said.
The researchers noted that air pollution is a cocktail of many toxic components, but particulate matter, especially ambient fine particles such as PM2.5, are the most concerning in terms of causing detrimental health effects.
Ultrafine particles, in particular, are able to escape the body's protective systems, including sentinel immune cells and biological barriers, they said.
Recent evidence has revealed a strong link between high levels of air pollution and marked neuroinflammation, Alzheimer's-like changes, and cognitive problems in older people and even in children, according to the researchers.
The researchers found that inhaled particles can enter the bloodstream after crossing the air-blood barrier, eventually reaching the brain, and leading to damage of the brain-blood barrier and surrounding tissues as they do so.
Once in the brain, the particles were hard to clear and were retained for longer than in other organs, they said.
The study offers new evidence to prove the risks of particulate pollution to the central nervous system.
However, the researchers recommend that more investigation is needed into the mechanics of how inhaled ambient fine particles reach the brain.
- wellnessAir Pollution Linked With More Severe COVID-19: Study
- wellnessAir Pollution Led To 100,000 Premature Deaths In India Over 14 Years, Finds UK Research
- wellnessAir Pollution 2nd Biggest Health Risk In India, Annual Economic Cost Over USD 150bn: Report
- healthWorld Environment Day 2021: Harmful Effects Of Air Pollution On The Environment
- disorders cureCOVID-19: Air Pollution May Affect Coronavirus Lethality, Study Says
- prenatalAir Pollution Can Increase The Risk Of Miscarriage, Studies Suggest
- wellnessLung Diseases Caused By Breathing In Polluted Air
- newsHow Electric Rickshaw Pullers Are Countering Pollution