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Diabetes Risk in Kids During Pregnancy
"We
know
that
children
born
to
women
with
type
2
diabetes
or
gestational
diabetes,
or
who
have
high
blood
sugar
during
pregnancy
are
at
risk
of
becoming
diabetic
themselves.
This
study
suggests
that
the
childrens'
increased
risk
appears
to
be
due,
at
least
in
part,
to
their
prenatal
exposure
to
relatively
high
maternal
blood
glucose," said
study
co-author
Paula
Chandler-Laney,
a
post
doctoral
fellow
at
the
University
of
Alabama
at
Birmingham.
Chandler-Laney and her colleagues did a research on 21 children between an age of 5 to 10 years and tested the childrens' sensitivity to insulin, the hormone that regulates sugar in the blood.
They further checked the medical records of mothers of the children to look into maternal blood sugar concentration during the oral glucose tolerance test.
At this the experts discovered there was a reverse formation between blood sugar of the mother and the child. Which means higher the mother's blood sugar levels during pregnancy lesser was her child's insulin sensitivity, which is a major risk factor for type 2 diabetes.
Obesity lowers insulin sensitivity, but the child's reduced insulin sensitivity was independent of their amount of body fat, the authors reported.
In addition, children with high blood sugar levels, while they are in the womb, will have exaggerated insulin secretion after a meal , independent of their reduced insulin sensitivity. Apparently high insulin secretion is also associated with increased risk for later development of type 2 diabetes, Chandler-Laney explained.
In the beginning children do not high blood sugar but at the time puberty insulin sensitivity will reduce, she noted.
"High maternal blood glucose during pregnancy may have lasting effects on childrens' insulin sensitivity and secretion, potentially raising the risk for type 2 diabetes," Chandler-Laney said.
"Obstetricians, pediatricians, and pregnant women should all be aware of the potential far-reaching consequences that elevated blood sugar during pregnancy can have on childrens' health," added Chandler-Laney.
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