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Japanese Encephalitis Causes 48 Deaths In Assam: What You Should Know About The Disease
In Assam, the outbreak of Japanese encephalitis has caused 48 deaths so far, with the state government taking all proactive steps to control the situation. Most of the upper Assam districts, including Golaghat, Jorhat, Dibrugarh, Lakhimpur and the lower Assam district of Kamrup have been affected by the mosquito-borne disease.

What Is Japanese Encephalitis?
Japanese encephalitis is a mosquito-borne viral infection [1] . It is the leading cause of viral encephalitis in Asia with an estimated 68,000 clinical cases reported every year, according to the World Health Organization (WHO).
Flavivirus that causes Japanese encephalitis, belongs to the Flaviviridae family. It is the same genus of viruses responsible for the yellow fever and dengue [2] .
What Causes Japanese Encephalitis
The Culex mosquito transmits the virus to humans and they become the carriers of the virus. The mosquito can infect animals too. Wild birds and domestic pigs are likely to be the natural hosts of Japanese encephalitis, and mosquitoes are the vectors.

Symptoms Of Japanese Encephalitis
Japanese encephalitis has no symptoms. However, if there are symptoms, they will appear 5 to 15 days after being infected. A person with mild Japanese encephalitis might get symptoms like headache and a fever.
But in serious cases the symptoms are as follows:
- Headache
- Fever
- Nausea
- Vomiting
- Tremors
- Stiff neck
- Spastic paralysis
There might be changes in the brain function as well, causing coma, stupor, disorientation, and convulsions in children. These symptoms could lead to lifelong complications like deafness, weakness on one side of the body, and uncontrollable emotions.
Risk Factors Of Japanese Encephalitis [3]
- Children are more likely to get affected by the virus.
- In temperate regions, the transmission of the virus is higher during the summer and early fall season, usually between May and September.
- In tropical areas, virus transmission might happen at any time of the year.
- In subtropical and tropical areas, the season depends on the rainfall and the patterns of bird migrations.
- Japanese encephalitis is more common in areas where people grow rice.

Diagnosis Of Japanese Encephalitis
The doctor will examine the symptoms, if there are any and check where the person lives. He/she might ask about the places they visited from where the recent infection could have emerged.
If the disease is suspected, the patient will undergo tests like an MRI scan and a CT scan [4] . The physician also might use a lumbar puncture to draw fluid from the spine, to verify the virus.
To detect human antibodies, immunofluorescence tests are done with the help of a fluorescent chemical.
Treatment Of Japanese Encephalitis
According to the World Health Organization (WHO), there is no antiviral treatment for patients with this disease. Antibiotics are only available to relieve you from the symptoms.
Prevention Of Japanese Encephalitis
To prevent Japanese encephalitis, one should get a vaccination and use an insect repellent.
Vaccination [5]
The vaccination consists of two doses which are given through injections.
The second dose will be given 28 days after the first dose. An accelerated vaccination schedule is possible, in which only 7 days pass between the two doses and it's safe for people between 18 and 65 years of age.
The vaccination for Japanese encephalitis can cause short-term side effects like headache, muscle pain, red, swollen, and sore skin at the site of injection, hives, and breathing difficulties.
Doctors recommend vaccination for the following people:
- People who are travelling to areas where the disease is endemic.
- People who go for short-term trips lasting less than a month.
- People visiting areas where there is an outbreak.
- People participating in outdoor activities in an endemic area.
Other ways to prevent Japanese encephalitis are as follows:
Disclaimer: The information provided in this article is for general informational and educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or a qualified healthcare provider with any questions you may have regarding a medical condition.
- People who spent most of the time outdoors in the rural areas should use mosquito nets and wear protective clothing.
- Remove accumulated standing water nearby your house, as it is the breeding ground for mosquitoes.

- [1] Solomon, T., Dung, N. M., Kneen, R., Gainsborough, M., Vaughn, D. W., & Khanh, V. T. (2000). Japanese encephalitis.Journal of Neurology, Neurosurgery & Psychiatry,68(4), 405-415.
- [2] Mackenzie, J. S., Gubler, D. J., & Petersen, L. R. (2004). Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses.Nature medicine,10(12s), S98.
- [3] Libraty, D. H., Nisalak, A., Endy, T. P., Suntayakorn, S., Vaughn, D. W., & Innis, B. L. (2002). Clinical and immunological risk factors for severe disease in Japanese encephalitis.Transactions of the Royal Society of Tropical Medicine and Hygiene,96(2), 173-178.
- [4] Kalita, J., & Misra, U. K. (2000). Comparison of CT scan and MRI findings in the diagnosis of Japanese encephalitis.Journal of the neurological sciences,174(1), 3-8.
- [5] Oya, A. (1988). Japanese encephalitis vaccine.Pediatrics International,30(2), 175-184.



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