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Sushmita Sen Opens Up About Her Fight With Addison's Disease: Know About The Auto Immune Condition
In a recent post on her YouTube channel, Sushmita Sen, a fitness enthusiast, former beauty queen and actor revealed that she was diagnosed with an autoimmune condition called Addison's disease in 2014.
And yesterday, Sushmita updated about her health condition, stating that she had suffered a heart attack but is much better now.
The supermom added that in order to fight the disease and the associated fatigue, she began meditating with Nunchaku (a Japanese martial arts tool) to overcome chronic disease. Today, we will look at what Addison's disease is and how it can affect one's body and overall health.
Addison's disease is also called adrenal insufficiency. It is a rare disorder and develops when your body doesn't produce certain hormones in the required quantity. The adrenal glands are located on top of your kidneys and produce the necessary hormones required for your (normal) bodily functions.
So, the disease occurs when the adrenal cortex gets damaged and fails to produce the required amount of steroid hormones cortisol and aldosterone. The hormone cortisol regulates one's body's reaction to stressful situations and aldosterone aids the regulation of sodium and potassium levels in your body [1][2].
Addison's disease can develop in individuals of any age group and can affect both men and women equally. The condition can be life-threatening if left untreated. Addison's disease is named after Thomas Addison, the British physician who first described the condition in On the Constitutional and Local Effects of Disease of the Suprarenal Capsules (1855).
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Symptoms Of Addison's Disease
The condition usually develops gradually and can take more than two to three months. As the symptoms of the condition develop on a slow basis, it is often ignored until an injury or an illness worsen the symptoms [3].
The symptoms of Addison's disease include the following [4]:
- Nausea
- Extreme fatigue
- Low blood sugar (hypoglycaemia)
- Weight loss and decreased appetite
- Darkening of your skin (hyperpigmentation)
- Low blood pressure, even fainting
- Salt craving
- Muscle or joint pains
- Diarrhoea
- Vomiting
- Abdominal pain
- Depression or other behavioural symptoms
- Irritability
In women, it can cause body hair loss and sexual dysfunction. People with the condition are prone to experiencing neuropsychiatric symptoms. When left untreated, the condition can worsen to Addisonian crisis which can cause agitation, visual and auditory hallucinations and delirium.
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If
the
condition
worsens
and
develops
the
following
symptoms,
you
must
immediately
get
medical
help
[5].
- High fever
- Confusion and fear
- Restlessness
- Loss of consciousness
- Sudden pain in the lower back, belly, or legs
Causes Of Addison's Disease
The condition develops due to damage in your adrenal glands which results in the lack of production of the hormones. There are two major classifications for the cause of Addison's disease and they are as follows [6]:
Primary adrenal insufficiency: This occurs when the when there is severe damage to your adrenal glands and are unable to produce hormones. Primary adrenal insufficiency caused when the immune system attacks the adrenal glands.
This can also develop due to prolonged administration of glucocorticoids, infections, cancer and abnormal growths (tumours) and certain blood thinners used to control clotting in the blood.
Secondary adrenal insufficiency: This occurs when the pituitary gland fails to produce the adrenocorticotropic hormone (ACTH) required for the release of hormones. Most symptoms of secondary adrenal insufficiency are similar to those of primary adrenal insufficiency.
Secondary adrenal insufficiency can also develop due to medications, tumours, genetics and a traumatic brain injury.
Risk Factors For Addison's Disease
Individuals with the following aspects are prone to developing Addison's disease more [7]:
- Cancer
- Autoimmune disease, like type 1 diabetes or Graves' disease
- Chronic infections like tuberculosis
- Have had surgery to remove any part of your adrenal gland
- Takes anticoagulants (blood thinners)
Diagnosis Of Addison's Disease
To understand and examine the condition, the doctor will begin by examining your medical history and the signs and symptoms.
Once done, the doctor may carry out the following tests [8]:
- ACTH stimulation test
- Blood test
- Insulin-induced hypoglycaemia test
- Imaging tests
Treatment For Addison's Disease
The medical care required for the condition will be dependent on the cause behind it.
Medicines for regulating the adrenal glands may be prescribed. A combination of glucocorticoids medications i.e. drugs that stop inflammation will be prescribed as it can help improve your overall health.
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Apart from that, hormone replacement therapy is the most effective measure to correct the levels and clear the imbalance of steroid hormones in your body [9].
Alternative
therapies
such
as
yoga
and
meditation
can
be
helpful
as
it
can
help
control
and
manage
your
stress
levels.
But,
talk
to
your
doctor
before
adopting
alternative
methods
to
treat
your
condition
[10].
Increase (in moderation) the level of salt in your diet, for the required sodium levels.
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