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Hypogonadism – Lack of Gonadal Hormones
Lack of gonadal hormones (Testosterone in men and Oestrogen in women) is called Hypogonadism and when this happens due to lack of Pituitary hormone it is called secondary hypogonadism. Normally two Pituitary hormones known as LH and FSH are responsible for stimulating Testes and Ovaries in men and women respectively.
What are the clinical features of lack of hypogonadism?
In Men
Loss of body, facial and pubic hair
Increased breast tissue (gynaecomastia)
Reduced testicular size
Smooth, fine wrinkly skin, especially on the face
In Women
Decrease in size of breast
Lack of pubic and axillary hairs
Absent or irregular period
What are the tests required for hypogonadism?
1.Blood Investigations
* LH, FSH, Prolactin
* Testosterone/ Estradiol
2.Imaging MR scan
What are the treatment options for hypogonadism?
For men - Androgen replacement orally or by injection.
For women - Cyclical estrogen progesterone preparations
Gonadotrophin preparations
Disclaimer: The information provided in this article is for general informational and educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or a qualified healthcare provider with any questions you may have regarding a medical condition.
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