Energy Matters: Managing Fatigue and Staying Active during Blood Cancer Treatment

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There is a kind of tiredness that sleep cannot fix. It lingers even after a full night's rest. It slows down simple tasks like getting out of bed, holding a conversation, or finishing a meal. For many people undergoing treatment for blood cancers, this isn't occasional exhaustion; it becomes part of daily life.

Fatigue is one of the most common and distressing symptoms during cancer treatment. Yet, it often goes unspoken. Patients may assume it is "normal" and something they simply have to endure. Caregivers may struggle to understand why their loved one feels drained despite doing "so little." What many don't realise is that cancer-related fatigue is not just physical tiredness; it affects emotions, thinking ability, sleep patterns, and overall motivation.

Recognising, assessing, and managing fatigue can significantly improve quality of life during treatment. Energy may feel limited, but with the right approach, it can be protected, restored, and used wisely. We spoke to Dr Sachin Sekhar Biswal, Consultant - Medical Oncology, Manipal Hospital, Bhubaneshwar, who shared insights on the same.

Understanding Cancer-Related Fatigue

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"Cancer-related fatigue (CRF) affects nearly 60-90% of oncology patients. The onset may precede diagnosis and may last even after treatment completion. Not only patients with active treatment but also survivors often complain about fatigue. Cancer-related fatigue (CRF) is characterised by diminished energy, increased need to rest, generalised weakness, diminished mental concentration, insomnia, or increased daytime sleepiness and emotional reactivity," explained Dr Biswal.

Why Blood Cancer Patients Face Unique Challenges

Fatigue is particularly complex in hematologic malignancies such as:

• Multiple Myeloma
• Acute Leukemia
• Chronic leukemia

"These cancers directly affect the blood-forming system. Many patients present with anaemia and infections, both of which significantly worsen fatigue. Additionally, treatments for these cancers are often intensive, especially in the early phases, which can further contribute to weakness and low energy," added Dr Biswal.

Chemotherapy itself may lower blood counts, adding another layer of exhaustion and making it harder to maintain treatment continuity.

Managing Fatigue: A Multi-Pronged Approach

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The multifaceted spectrum of Cancer-related fatigue makes it challenging to identify the inciting factor and corrective measures exactly suited on a case-by-case basis. Therefore, the treatment usually consists of both pharmacologic and non-pharmacologic interventions as well as supportive care for co-existing conditions, such as anaemia and infections.

• Among non-pharmacologic interventions, medical nutrition therapy, Cognitive Behavioral Therapy (CBT), and exercise are the main interventions resulting in maximal benefit.
• Among pharmacologic interventions, erythropoiesis-stimulating agents, ginseng, and psychostimulants constitute important aspects.

The identification and treatment of fatigue is crucial to initiate early intervention and improve the quality of life of cancer patients.

Disclaimer: The information provided in this article is for general informational and educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or a qualified healthcare provider with any questions you may have regarding a medical condition.