Why The World Doesn't Seem Blur While Running?

Disorders Cure

oi-Staff

By Staff

Monday, December 22, 2008, 15:34

Ever wondered why your vision is not altered when we catch speed while running? No matter how fast we move or run, our eyes, head and body immediately adjust themselves according to our speed, and now scientists have uncovered the phenomenon underlying this unique ability, called vestibular-ocular reflex (VOR), in humans.

In their new study, researchers at the Salk Institute for Biological Studies explain how the vestibular-ocular reflex, which keeps us and the world around us stable, achieves the accuracy it is famous for . The scientists said that signals from the vestibular system of the inner ear, which detects motion, are relayed in a linear fashion no matter how fast the neurons are firing, quite unlike other signals in the brain, whose transmission is frequency-dependent.

"Most of what we know about signal transmission between neurons comes from studying special cortical or hippocampal neurons, but many vital functions, such as balance and breathing, are controlled by neurons in the brain stem, which, as we discovered, work very differently. Pursuing the mechanisms that control neurons in the brain stem is important for developing new classes of biotherapeutic agents," said Howard Hughes Medical Institute investigator Sascha du Lac, Ph.D., an associate professor in the Systems Neurobiology Laboratory.

The researchers mainly dealt with a simple type of learning: How does the brain learn to stabilize an image on the retina and use eye movement to compensate for a moving head? The VOR has to be fast and for having a clear vision; head movements must be compensated for almost immediately.

For reaching the ideal speed, the VOR-circuit involves only three types of neurons: sensory neurons, which detect head movement; motor neurons, directing eye muscles to relax or contract; and so-called vestibular nucleus neurons in the brainstem that link the two.

Though, the reflex time is short due to the brevity of the circuit, it was less clear what qualities of the circuit ensure that eye velocity is precisely matched to head velocity. As the VOR operates accurately regardless of how fast we move our head, scientists long expected that the signal transmission at the synapses-specialized points of contact between nerve cells-that connect the sensory onto the vestibular nucleus neurons would be linear.

But, transmission at most synapses is non-linear. brain cells signal by sending electrical impulses along axons, long, hair-like extensions that reach out to neighboring nerve cells. When an electrical signal reaches the end of an axon, the voltage change triggers release of neurotransmitters, the brain''s chemical messengers. Then, the neurotransmitter molecules travel across the space between neurons at a synapse and trigger an electrical signal in the adjacent cell-or not.

"Most known synapses act as information filters, and both the probability and the extent of neurotransmitter release as well as the efficacy of the postsynaptic response depend heavily on the recent history of the synapse. But no matter whether you go jogging or watch TV on your

was found that same amount of neurotransmitter was released; no matter how fast the sensory neuron was firing. And instead of vacillating, the post-synaptic neuron took the information and transmitted it faithfully.

The study was published in the current issue of the journal Neuron.

Disclaimer: The information provided in this article is for general informational and educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or a qualified healthcare provider with any questions you may have regarding a medical condition.