Just In
- 9 min ago Thrissur Pooram 2024: Date, Time, History, Significance, And Celebrations Related To Kerala's Rich Traditions
- 4 hrs ago Daily Horoscope, 19 April 2024: Gemini Will Have A Controversial Day In Terms Of Love
- 7 hrs ago Kamada Ekadashi 2024 Wishes: Greetings, Messages, Texts, Images, Twitter Status And Instagram Captions
- 8 hrs ago Deepika Padukone's 6 Refreshing Skincare Tips to Beat the Summer Heat
Don't Miss
- Finance New Rules Mandate Aadhaar For Small Savings Schemes
- News Nagaland Lok Sabha Election 2024: Polling Commences For Lone Parliamentary Seat
- Movies Aavesham Box Office Collection Day 9 Prediction: Fahadh Faasil's Movie Likely To Continue Successful Run
- Technology Nothing Phone 2 Receives NothingOS 2.5.5 Update with ChatGPT Integration and More
- Sports LSG vs CSK IPL 2024: Ekana Stadium Pitch Report, Lucknow Weather Forecast & Live Streaming Info
- Automobiles Aprilia RS 457 Accessories: A Detailed Look At The Prices
- Education Karnataka SSLC Result 2024 Soon, Know How to Check Through Website, SMS and Digilocker
- Travel Telangana's Waterfall: A Serene Escape Into Nature's Marvels
Study Finds Cholera Vaccines Less Effective For Children Under Five
A study has found that vaccines for cholera are less effective for children under five.
Amidst Cholera vaccines provide significantly less protection for children under the age five, a population particularly at risk of dying from the diarrhoeal disease, a study has found.
A team of researchers at Johns Hopkins University in the US conducted a review of literature, which considered seven clinical trials and six observational studies.
The study found that the standard two-dose vaccine regimen reduced the risk of getting cholera on average by 58 percent for adults but only by 30 percent for children under age five.
How Does Cholera Spread?
Cholera is transmitted through an oral-fecal route, with outbreaks and endemic transmission tending to occur in areas with poor sanitation and a lack of clean drinking water.
Cholera affects an estimated three to five million people per year worldwide and causes 28,000 to 130,000 deaths annually. Vaccines for this illness cost an average of USD 1.85 per dose. Oral vaccines for cholera, which are composed of killed, whole cells of the bacteria Vibrio cholerae, became commercially available shortly after their development in the 1980s.
"Yet for years, these vaccines have not been widely available, have been fairly expensive for broad public health use and have been associated with a number of misconceptions, including that they do not work well," said Andrew Azman, research associate at John Hopkins University.
Studies have suggested a wide range of how well these vaccines provide protection, with some results suggesting that the risk of cholera is cut in half with the vaccine and others suggesting that risk is nearly eliminated.
"There continues to be a lot of misinformation on what this vaccine is and what it can do," Azman said.
The team searched for any randomised controlled trials and observational studies that examined this data for oral cholera vaccines. The trials and studies involved more than 500,000 thousand participants combined.
Taking an average of the results, researchers found that for a two-dose regimen - the standard for these vaccines - efficacy was 58 percent and effectiveness was 76 percent. However, for children younger than 5, efficacy was substantially lower: around 30 per cent.
One dose of these vaccines appeared to provide similar protection as a two-dose regimen, at least within the six months following vaccination, researchers said.
The study was published in the journal The Lancet Infectious Diseases.
- wellnessDiarrhoea Outbreak: Public Health Emergency Declared In Karaikal, Schools And Colleges Shut For Three Days
- wellnessWorld Toilet Day 2020: Infections You Can Catch From A Dirty Toilet
- wellnessCoronavirus: 9 Germiest Places In Your Workplace You Should Be Aware Of!
- wellnessWhy Drinking Iced-tea Is Bad For You
- shirdi sai babaShri Sai Satcharitra - Part 3 Of Chapter 23
- health4 Diseases You Can Take Vaccine For Even After You Turn 40: Is It Too Late to Get Hepatitis B Vaccine?
- healthNobel Prize 2023: Scientists Behind The COVID-19 mRNA Vaccines Wins
- healthCOVID-19 Vaccines and Heart Attacks: New Studies Show Different Results; What Are They?
- healthCancer, Heart Disease Vaccine To Be Ready By 2030: Know More Here
- healthXBB.1.16: Symptoms; Are Vaccines Useful? WHO Concerned Over Recent COVID Spike In India
- wellnessNational Vaccination Day: List Of Vaccines Every Adult Over 50 Should Get
- disorders cureNational Vaccination Day 2023: Diseases For Which No Vaccines Are Currently Available