- 1 hr ago Navratri 2022: 5 Ways To Detox After Navratri Celebrations
- 1 hr ago Durga Puja 2022: Alia Bhatt To Bipasha Basu, Durga Puja Outfits Guide From Bollywood Beauties
- 2 hrs ago Navratri 2022: Four Famous Akhand Jyoti Temples
- 2 hrs ago Malavika Mohanan's Beauty Routine: A Combo Of Her Malayali Roots And Holistic Care
- News Kerala govt opposes plea challenging reservation policy and fee waiver in KSCSA
- Technology Infinix Note 12i 2022 With 6.7-inch AMOLED, Helio G85 Launched
- Finance RBI Policy: MSME To Have Dual Headwinds, Rising Inflation & Rising Interest Costs: Analyst
- Sports Transfer Rumours: Erling Haaland still on Real Madrid radar
- Movies Vivek Agnihotri Labels Koffee With Karan ‘Artificial'; Reasons Out Why He Would Never Appear On The Show
- Automobiles BYD Inaugurates New Showroom In Jaipur - Expands Operations Ahead Of Atto 3 Electric SUV Launch
- Travel The Fergana Valley: A Picturesque Ethnic Melting Pot
- Education JALDOOT App: An App to Make Farmers Prosper and Villages Grow
Scientists have found the first indications that some of the neurological symptoms of long-COVID are being caused by protein clumps appearing in the brain that are similar to those that lead to Alzheimer's disease and dementia.
The study, published in the journal Nature Communications, shows similarities between the effects of COVID-19 and the early stages of neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
The researchers cautioned that the implications of the changes were unclear and did not necessarily suggest people might have lasting damage or that the changes might profoundly affect thinking, memory or other functions.
If further studies confirm that amyloid clumps are contributing toward long-COVID, then drugs which have been developed to combat Alzheimer's and Parkinson's may be repurposed to treat these debilitating neurological symptoms, the researchers said.
"It may be possible that existing drugs may be used to treat the brain fog that affects a significant portion of people who go on to experience long-COVID having been infected with SARS-CoV-2," said Nick Reynolds from La Trobe University in Australia.
Long COVID is marked by neurological symptoms such as memory loss, sensory confusion, severe headaches, and even stroke in up to 30 per cent of cases, which can persist for months after the infection is over.
While there is evidence that the virus can enter the brain of infected people, the precise mechanisms causing these neurological symptoms are unknown. The researchers investigated if similar amyloid clumps could be formed from fragments of protein from SARS-CoV-2.
They found two such protein fragments that readily form amyloids, called ORF6 and ORF10, and that these are highly toxic to brain cells grown in a lab.
Reynolds said the findings of aggregates of SARS-CoV-2 proteins in people with long COVID may explain the condition known as "brain fog".
"These toxic clumps of protein, or amyloid assemblies, appear to be similar to those found in Alzheimer's disease and may be responsible for some of the neurological symptoms of long-COVID," Reynolds said.
"We suggest that aggregates of SARS-CoV-2 proteins may trigger neurological symptoms in COVID-19 that many call brain fog," he added. PTI SAR SAR
- basicsWhat Is Pregnancy Brain? Symptoms, Causes And Management
- wellnessCoronavirus Residues Might Be Causing Long COVID: New Study
- kidsLong COVID In Children Can Last At Least Two Months: Study
- wellnessLong Covid-19 Risk Less With Omicron Than Delta Variant, UK Study Finds
- wellnessCovid-19 Infection May Induce Severe Bone Loss, Animal Study Suggests
- wellnessEven Vaccinated People Can Develop Long Covid, Study Finds
- wellnessPost-COVID Fatigue Is More Than Just Tiredness; Could It Be Chronic Fatigue Syndrome, Or Long COVID?
- disorders cureLung Abnormalities Found In Long COVID Patients With Breathlessness: Study
- healthOmicron Natural Vaccine? Experts Call Notion Dangerous, Say Doesn’t Take Long Covid Into Account
- healthLong Covid May Not Be As Fatal As Acute COVID-19 But Can Worsen Existing Ailments, Say Experts
- healthOrthopedist Explains Symptoms And Gives Advice On Long COVID-19
- disorders cureCOVID-19: What Is Long COVID? Most Common Post-COVID Symptoms And How To Manage It