- 14 min ago Trisha Krishnan Looks Alluring As Princess Kundavai In Ponniyin Selvan
- 2 hrs ago Priyanka Chopra In Backless Black Dress Looked Like A Glam Diva; Gave Chic Fashion Goals
- 2 hrs ago Durga Puja 2022: Navapatrika Puja Date, Time, Significance, And Symbolism of Nine Plants
- 9 hrs ago Daily Horoscope, 24 September 2022: Today's Horoscope Predictions For All Zodiac Signs
- Education CUET PG Final Answer Key 2022 Available Now: Download Answer Key PDF and Know the Result Release Dates here!
- Sports The 'Fedal' feelings! Tearful Rafael Nadal bids emotional adieu to Roger Federer
- Automobiles 5 New Car Launches In The Coming Weeks - Grand Vitara, MG Hector Facelift & More
- Finance Prabhudas Lilladher: Buy Rallis India Stock With Target Price Of Rs. 250
- News Why is #XiJinping trending on Twitter?
- Technology Amazon OnePlus Nord Watch Quiz Answers; Win Rs. 10,000 Prize
- Movies Brahmastra: Mouni Roy Reveals If She Will Return As Junoon For Parts 2 And 3
- Travel Shanghai: Mainland China At Its Best
The role of genetics in determining whether a particular type of cancer has been inherited or has occurred due to environmental factors such as exposure to radiation is phenomenal. While the root causes of many types of cancers remain unknown, Oncologists and researchers are using genetic testing and Cancer genomics to customize treatment and administration of drugs to target the cancerous cells better without causing any damage to the healthy cells and analyze the risk of other cancers.
Genes and Cancer Risk
Many consider cancer as a random disease wherein the flawed cells in the body, due to their severity and place of origin, can cause cancer. It is a genetic disease that is caused when certain changes take place in our genes which control the functioning of the cells, and the ways they grow and divide. The DNA in our body is known as the genetic blueprint in each cell. Genes help pass on inherited traits like height, eye colour or hair colour from the parents to the child. Similarly, these genes can also affect the kind of diseases that the child is likely to suffer from, including cancer. Mutations or changes in the genes play a crucial role in the development of cancer as they can cause the protein in the cell either to grow or divide into new cells. When this mutation causes cells to grow uncontrolled, it can lead to cancer.
In each person's cancer cells, the genetic changes are unique and will continue to change further as the cancer cells grow. Therefore, any patient diagnosed with cancer must know their family history to determine the risk of inherited mutation and the development of other cancers. The most common types of cancers that may be at risk of being inherited mutation are breast cancer, endometriosis cancer, prostate cancer, pancreatic cancer and ovarian cancer.
Cancer is often referred to as a "family-run" disorder that can easily make the patient and the family members anxious about passing on the trait or finding out the truth about inherited mutations. Sometimes, post-diagnosis of cancer, the doctor may perform tests to look for mutations in the genes. In such cases, Genetic Testing can help look for certain types of mutations or changes in the genes and understand the risk factors. There are different types of genetic tests conducted, including predictive genetic testing to look for inherited gene mutations in people with a higher risk of getting some kind of cancer. This type of testing is recommended for patients with a family history of particular types of cancer, and to check if those cells carry a gene mutation that increases their risk. For patients already diagnosed with cancer, genetic testing can assess factors that indicate cancer is caused by an inherited mutation and risk of some other cancers, and for family members of a person who is known to have an inherited mutation that increases cancer risk.
BRCA mutation testing: BRCA gene test can help determine if there are any changes in the DNA that can increase the risk of breast cancer, ovarian cancer, pancreatic cancer, prostate cancer, and melanoma.
FAP test: This test is done to find out about familial adenomatous polyposis (FAM), a genetic condition. This is diagnosed when a person develops multiple colon polyps and is likely to develop colorectal cancer. Patients with FAP have an increased chance of developing cancer in the other organs including the stomach, pancreas, small intestine, and biliary tree. There is also a risk of hepatoblastoma (a rare type of liver cancer) associated with children with FAP. It must be kept in mind that not all the symptoms of FAM indicate cancer.
HNPCC (Hereditary Non-polyposis Colorectal Cancer) Test: This test is done to find out the chances and risks of developing colorectal cancer as an inherited mutation with a family history of HNPCC and can grow cancerous in other organs including ovaries or uterus, GI tract, kidneys or urinary tract.
Genetic testing is usually recommended for people with a certain pattern of cancer found in the family. For instance, first, of kin relations (parents and siblings, children) with cancer, relatives with the same type of cancer, a cluster of cancer linked to a single gene mutation, a family member with more than one type of cancer, a family member with childhood cancers or rare cancers, etc. are at risk and must be tested.
On A Final Note...
It is important to know your family medical history and be cautious about any risk of developing cancer. If you notice any symptoms of a particular type of cancer, seek medical help and talk to your physician immediately.
- wellnessNational List Of Essential Medicines (NLEM) 2022: Popular Antacid And 25 Medicines Removed, Full List
- wellnessGlucose Metabolism Is Surprisingly Normal In Cancer, Says New Study
- wellnessCervical Cancer Vaccine: All You Need To Know About India's Self-Developed HPV Vaccine
- wellnessSmoking, Alcohol & High BMI Are Primary Risk Factors For Cancer Death: Study
- healthScientists Develop Smart Contact Lenses That Can Diagnose Cancer From Tears
- disorders cureMen At Higher Risks Of Most Cancer Types Than Women: Insights From New Study
- zodiac signsVenus Transit In Cancer On 07 August 2022: Impact On Zodiac Signs And Remedies
- wellness'Tobacco Causes Painful Death': New Health Warning From December 1 On Tobacco Packs
- wellnessGerman Scientists Develop Bacterial Microrobots To Combat Cancer Without Any Pain And Tears
- wellnessScientists From Japan Genetically Engineered Parasitic Worms To Detect And Kill Cancer Cells
- wellness'Next-Gen' Cancer Therapy Can Kill Tumours Without Harming Healthy Cells
- zodiac signsJuly Born: Health, Interesting Qualities, And Compatibility With Other Zodiac Signs