Just In
- 1 hr ago Aditi Rao Hydari Marries Siddharth, Exploring Heeramandi Star's Ethnic Style Statements, Bookmark Now!
- 3 hrs ago Solar Eclipse 2024 Date And Time: Will It Be Visible In India? When And Where To Watch It, Deets Inside!
- 4 hrs ago Balenciaga Tape Bracelet: Is It Worth Spending A Bomb On Adhesive Looking Accessory? Know Our Take!
- 7 hrs ago In China, GenZ Workers Are Ditching Formal Attire For Pyjamas, Know The Reason Behind This
Don't Miss
- News 'ED Can Keep Me As Long As It Wants. It's A Scam', Asserts Kejriwal In Court; Remand Extended Till April 1
- Finance Closing Bell: Market Ends With Gains; Sensex & Nifty Post Best Week In 2 Months; Banks Lagged Behind
- Movies Aditi Rao Hydari Shares First PIC With Siddharth After Their Secret Wedding News Goes Viral; Says, He Said Yes
- Automobiles Kia EV9 Crowned World Car Of The Year At 2024 Awards, Showcasing EV Dominance
- Education OAVS Teacher Direct Recruitment 2024; Apply online for 1386 Posts, Check out for more details
- Sports RCB vs KKR Head To Head Stats, Results & Record in M Chinnaswamy Stadium, Bengaluru Ahead of IPL 2024 Match 10
- Technology OPPO F25 Pro New Coral Purple Colour Variant Launched in India; Where to Buy?
- Travel Explore Tamil Nadu's Diverse Wedding Venues
German Scientists Develop Bacterial Microrobots To Combat Cancer Without Any Pain And Tears
Cancer treatment is still a challenge; though traditional cancer treatment methods like chemotherapy and immunotherapy have lowered mortality and morbidity rates to a great extent, they have their own limitations.
A cancer treatment method bacteriotherapy, either used alone or in combination with any traditional method, is known to show positive effects in inhibiting the progression of cancer cells and shows promising effects in the treatment of cancer. [1]
The scientists from the Max Planck Institute for Intelligent Systems (Germany) claim to have created a cutting-edge bacteria-mediated therapy to treat cancer-spreading tumours by magnetically directing the bacteria as microrobots to deliver drugs to a specific location. [2]
Why Are Our Brains Smaller Than Our Ancestors'?
How Do Bacterial Microrobots Destroy Cancer Cells?
The bacterial microrobots quickly and painlessly kill cancer cells by releasing medications right into the tumours. As the medication is delivered right on the spot, there are very low chances of pain and toxicity, and higher chances of the drugs' effects in the required body area and not the entire body.
The study was carried out on 86 E. coli bacteria, the most common type of bacteria that resides in the intestines of the human body. These bacteria were turned into microrobots by attaching numerous nanoliposomes (lipid vesicles to store chemotherapeutic drugs) and magnetic nanoparticles (iron oxide) to control their movement when inside the human body.
Bacteria were linked to nanoliposomes and magnetic particles by the use of potent biomolecule binding agents named streptavidin-biotin complexes. The agent forms a stable and unbreakable bond and helps keep the attachments intact.
When the microrobots successfully reach and surround the tumour tissues, just by the use of infrared radiation in the location, the attached drugs can be released, which will not only kill the cancerous cells but also awaken the dormant immune system to fight against the cancer cells.
Meningococcal Meningitis Outbreak In The US Has Killed A Quarter Of People: All About The Condition
Is Bacteriotherapy Promising?
Bacteriotherapy is a 1700-year-old technique; numerous researchers have tried to give microbes access to anti-cancer medications, but they have failed as the technique is a bit tricky and requires ideal fusion of various techniques.
The researchers of the study, Mukrime Birgul Akolpoglu and her team, have successfully managed to make the common bacteria E. coli efficient enough through nanomachines for drug delivery.
They made a way so that nanoliposomes, which are attached to the bacteria, will only release the drugs after coming into contact with infrared radiation, leaving no scope for release of drugs at other locations due to some therapeutic interactions or natural bacterial secretion.
Additionally, the movement control is managed by integrating magnetic particles into perfect combinations.
These features talk about the promising effects of bacteriotherapy.
To Conclude
At the beginning of the month, scientists from Japan engineered the genetic codes of parasitic worms, Anisakis simplex, and modified them in a way so that they could deliver cancer-killing substances directly to the infected cells without being affected inside the body.
Such treatment methods can bring hope to cancer patients in the future and bring mortality rates down to a great extent.
- healthHow Dirty Is Your Phone? If Bacterias Could Speak They Would Have Said It Is Dirtier Than A Public Restroom!
- disorders cureRise In Antibiotic Resistance Among Indians Is The New Evolving Threat Amidst COVID-19 Pandemic: LANCET Study
- insyncAustralian Scientists Discover Superworms That Digest Styrofoam, Offering Hope For Plastic Waste Management
- disorders cureMeningococcal Meningitis Outbreak In The US Has Killed A Quarter Of People: All About The Condition
- disorders cureTyphoid-Causing Bacteria Have Become Increasingly Resistant To Essential Antibiotics: Lancet Study
- wellnessAMU Researchers Find 'Dangerous' Drug Resistant Bacterial Gene In Hospital Waste
- wellnessBacteria In Urine May Signal Aggressive Prostate Cancer: Study
- disorders cureWhat Are The Common Diseases Caused By Bacteria In Humans?
- disorders cureWhat Is Typhoid Fever? Causes, Symptoms, Risk Factors, Complications, Treatments And Prevention
- wellnessWorld Toilet Day 2020: Infections You Can Catch From A Dirty Toilet
- healthBacteria Part Of The Immune System Could Provide Antivirals Against COVID-19, Influenza
- disorders cureBrucellosis Outbreak In China: Bacterial Infection That Can Leave Men Infertile And Cause Fever