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Blood-thinning Drugs May Reduce Dementia Risk: Study
You might have heard from your elders or doctors talking about blood-thinning drugs and the reason you need to be careful about them. But a new study has found that blood-thinning drugs can actually be helpful as well.
According to the study, the blood-thinning drugs may not only prevent stroke in patients with abnormal heart rhythm, but also significantly reduce the risk of dementia.
The study had taken into consideration 444,106 patients. These participants were atrial fibrillation (AF) or abnormal heart rhythm patients and were taking anticoagulant drugs to prevent blood clots.
During the study it was found that these patients at the start had a 29 per cent lower risk of developing dementia than those who were not on anticoagulant treatment. When researchers at Karolinska Institute in Sweden looked at what happened during the period of time that the patients continued to take the drugs, they found an even bigger, 48 per cent reduction in the risk of dementia.
It looked at data from Swedish registries for patients between 2006 and 2014. The results strongly suggest that oral anticoagulants protect against dementia in AF patients, researchers said. "In order to prove this assumption, randomised placebo controlled trials would be needed, but such studies cannot be done because of ethical reasons. It is not possible to give placebo to AF patients and then wait for dementia or stroke to occur," they said.
AF is known to carry an increased risk of stroke and dementia, and anticoagulants have been shown to reduce the likelihood of stroke. Until now it was not clear whether anticoagulants could also prevent dementia, researchers said.
However, it was thought possible because if the drugs can prevent the big blood clots that cause stroke, they might also protect against the small clots that can cause unnoticed microscopic strokes that eventually lead to cognitive deterioration, they said.
Researchers identified all patients in Sweden who had a diagnosis of AF between 2006-2014. They checked on what drugs had been prescribed and dispensed following the diagnosis.
The researchers followed the patients' progress and this provided them with 1.5 million years of follow-up, during which time 26,210 patients were diagnosed with dementia.
When they first joined the study, 54 per cent of patients were not taking oral anticoagulants such as warfarin, apixaban, dabigatran, edoxaban or rivaroxaban.
The researchers found that the strongest predictors for dementia were lack of oral anticoagulant treatment, ageing, Parkinson's disease and alcohol abuse. They also found that the sooner oral anticoagulant treatment was started after a diagnosis of AF, the greater was the protective effect against dementia.
The study was recently published in the European Heart Journal and is considered as the largest ever to examine the link between anticoagulant treatment and dementia in AF patients.
Also learn about a few of the best foods to prevent dementia risk. Take a look.
1.
Leafy
Green
Vegetables:
Apart
from
being
rich
in
fibre
content,
leaft
green
vegetables
contains
folate
and
B9.
These
helps
in
reducing
depression
and
improve
cognition.
2.
Whole
Grains:
Rich
in
fibre
and
contains
all
the
essential
nutrients
that
helps
in
improving
cognition
and
prevents
dementia
risk.
Adding
whole
grains
in
your
daily
diet
is
very
essential.
3.
Omega-3
Fatty
Acids:
Omega-3
fatty
acids
are
the
good
fats.
Nuts,
certain
fishes,
olive
oil
and
flaxseeds
are
a
few
foods
that
are
rich
in
omega-3
fatty
acids.
Adding
these
foods
in
your
daily
diet
helps
to
reduce
the
of
having
brain
lesions
and
prevent
dementia.
(With Agency Inputs)
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