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Steroid Treatment May Prevent Miscarriages
Miscarriage or spontaneous abortion is the natural or spontaneous end of a pregnancy at a stage where the prenate is incapable of surviving, generally defined in humans at prior to 20 weeks of gestation. Miscarriage is the most common complication of early pregnancy.
Women
who
have
repeated
miscarriages
could
be
spared
the
misery
with
a
simple
steroid
treatment,
a
new
research
has
revealed.
Steroids
were
first
used
as
a
potential
treatment
by
Dr
Quenby
when
she
was
looking
for
ideas
to
help
Annette
Quinlan,
a
psychiatric
nurse
who
had
suffered
19
miscarriages
in
14
years.
During
the
British
Association
conference
in
Liverpool,
Dr.Siobhan
Quenby,
of
the
University
of
Liverpool
and
the
Liverpool
Women"s
Hospital,
said
that
tests
involving
120
women
had
identified
natural
killer
cells
as
a
cause
of
miscarriages
and
failed
IVF
embryo
implants.
Since
the
natural
killer
cells
can
destroy
infected
or
malignant
cells,
they
are
beneficial
in
most
of
the
body,
however,
in
the
uterus
they
have
been
found
to
promote
rapid
growth
of
blood
vessels
when
present
in
high
numbers.
The blood vessels transport additional oxygen-bearing blood and can cause miscarriages or prevent embryos implanting Steroids have been given to 40 women by Dr Quenby and three quarters of them have successfully given birth. All had previously had multiple miscarriages. The treatment has been shown to reduce the level of natural killer cells in the uterus, and this is thought to increase the chances of an embryo going to full term.
"If we have higher levels of natural killer cells in the uterus we have more blood vessels and more blood flow. We"ve been able to find a missing piece of the jigsaw of why some women have multiple miscarriages," Times Online quoted Dr Quenby, as saying.
For women in childbearing years, the chances of having a miscarriage can range from 10-25%, and in most healthy women the average is about a 15-20% chance. It is important for the expecting mothers to be well informed about a safe pregnancy and self-care methods, as it is a big responsibility to bring forth a new life in to the world. Steroids surely are god-send for parents who have faced the trauma of miscarriage many times.
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