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The Floppy Baby Syndrome
The currently incurable genetic diseases render most of the affected children severely paralysed and take the lives of the majority of these children before the age of one. This new treatment is an important step towards one day hopefully being able to better the lives of human patients.
A team at the Western Australian Institute for Medical Research (WAIMR) has restored muscle function in mice with one type of Floppy Baby Syndrome. The mice with Floppy Baby Syndrome were only expected to live for about nine days, but they managed to cure them and thus allowing them to live naturally and very actively into old age. Mice who were cured of the disease lived more than two years, which is very old age for a mouse.
Dr
Kristen
Nowak,
lead
author
on
the
publication,
said
the
team
was
extremely
encouraged
that
it
had
been
able
to
cure
a
group
of
mice
born
with
the
condition.
Dr
Nowak
said
the
team
was
able
to
cure
the
mice
with
the
recessive
form
of
the
genetic
condition
by
replacing
missing
skeletal
muscle
actin
–
a
protein
integral
in
allowing
muscles
to
contract
–
with
similar
actin
found
in
the
heart.
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