How Smoking Ups Heart Failure Risk

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Smoking is associated with thicker heart walls and reduction in the heart's pumping ability -- two factors linked to increased risk of heart failure, a new study warns.

That smoking is bad for heart has been known for long but the new study, in the American Heart Association's journal Circulation: Cardiovascular Imagin, reveals a clear mechanism by which tobacco may increase the risk of heart failure.

"These data suggest that smoking can independently lead to thickening of the heart and worsening of heart function, which may lead to a higher risk for heart failure, even in people who don't have heart attacks," said lead author of the study Wilson Nadruz Jr from Brigham and Women's Hospital in Boston, Massachusetts.

How Smoking Ups Heart Failure Risk


The study, conducted in participants of average age 75.7 and no obvious signs of cardiovascular disease, also found that higher rates of cumulative cigarette exposure -- measure of how much and how long people have smoked during their lifetime -- were associated with greater heart damage.

"The more people smoke, the greater the damage to the heart's structure and function, which reinforces the recommendations stating that smoking is dangerous and should be stopped," Nadruz Jr said.

The study examined data from 4,580 participants in the Atherosclerosis Risk in Communities (ARIC) Study who underwent an echocardiogram.

Even after accounting for factors such as age, race, body mass index, blood pressure, diabetes and alcohol consumption, current smokers had thicker heart walls and reduced pumping function, compared with nonsmokers and former smokers.

How Smoking Ups Heart Failure Risk


"The good news is that former smokers had similar heart structure and function compared with never smokers," senior study author said Scott Solomon, Professor at Harvard Medical School and Brigham and Women's Hospital, said.

"This suggests that the potential effects of tobacco on the myocardium might be reversible after smoking cessation," Solomon noted.

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