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Prolactin Hormone Disorder In Lactating Mothers
What causes prolactin hormone levels to go high ?
1.Drugs like Metoclopromide, Chlorpromazine, anti-depressants like Amitriptyline & Fluoxetine
2. Underactive thyroid gland
3. Prolactinomas - Prolactin-producing tumour of the pituitary gland. Prolactinomas occur most commonly in those under 40 years old. They are rare in children.
These prolactin tumors are about fives times as common in women as men. Lactating mothers face this problem usually. These tumors account for at least 30 % of all pituitary tumours.
What are the symptoms of Prolactin hormone disorder ?
In Men
1.Decreased
sexual
interest
Infertility
Impotence
Headache/
visual
changes
2.Infertility
3.Impotence
4.Headache/visual
changes
In Women
1.Abnormal
milk
flow
for
lactating
mothers
from
the
breast
not
related
to
nursing
or
childbirth
(galactorrhea)
2.Cessation
of
menses
not
related
to
menopause
3.
Infertility
4.Decreased
sexual
interest
5.
Headache/visual
changes
What
is
the
treatment
of
Prolactin
hormone
disorder?
Most patients with Prolactin tumours are treated with:
1.
Bromocriptine
(two
or
three
times
a
day).
2.Cabergoline
long
acting
and
requires
one
or
two
doses
per
week
Prolactin levels often fall to normal within a few weeks of starting the treatment. In women, once prolactin has fallen to normal, menstrual cycles usually resume and fertility is restored in most cases. In men, testosterone levels may rise to normal, which brings an improvement in sex life.
Rarely surgery is required when the tumors are resistant to treatment. Side effects of Bromocriptine are nausea, vomiting & constipation.
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